Dr. Joseph Culver is an Associate Professor in the Department of Radiology at Washington University. Dr. Culver’s lab explores ways of exploiting non-invasive optical measurements for both functional- and molecular- biological imaging. Specifically, Culver’s group develops subsurface optical tomography for imaging intrinsic, hemoglobin-sensitive contrasts, and exogenous, molecularly-targeted-fluorescent contrasts. Using hemoglobin contrasts, a portable and wearable brain imaging device is being developed to expand the range of human behaviors that can be assessed with functional neuroimaging techniques. In another project, fluorescence tomography systems and methods are being developed to image the bio-distribution of molecularly targeted probes in small animal models of disease.
Title: Optical imaging as a surrogate for fcMRI in mice and humans.