Dr. Hershey is a professor of Psychiatry, Neurology, and Radiology. Her research focuses on Neuropathophysiology underlying cognitive and mood aspects of Parkinson’s disease and other dopaminergic disorders, and Neuropathophysiological and behavioral effects of obesity and diabetes. Using neuroimaging (MRI, fMRI and PET) and neuropsychological techniques, the lab studies:
1) effects of severe hypoglycemia and hyperglycemia on the brain in children and adults with type 1 diabetes mellitus.
2) neurodevelopmental and neurodegenerative changes in Wolfram syndrome
3) relationship between obesity and dopamine receptors in the brain, their relationship to behavioral features and weight loss.
4) effects of Parkinson’s disease on cognitive and mood processes; how deep brain stimulation of the subthalamic nucleus affects brain function.
Title: Tracking Neurodegeneration in Wolfram Syndrome